Detralex 1000 mg Film‑Coated Tablets – Venous Circulation Support

Detralex 1000 mg Film‑Coated Tablets – Venous Circulation Support

Detralex 1000 mg Film-Coated Tablets (30 pcs) are a premium vascular health medication developed to help improve venous circulation and alleviate common symptoms associated with chronic venous insufficiency (CVI), varicose veins and hemorrhoidal disease. Each tablet contains a micronized purified flavonoid fraction (MPFF) consisting of diosmin and hesperidin, two natural citrus-derived bioflavonoids with venotonic and angioprotective properties.

This specialized formulation works by strengthening vein walls, enhancing venous tone, reducing capillary permeability and promoting improved microcirculation — all of which help support healthy blood flow in the lower limbs and relieve sensations of heaviness, swelling and fatigue in the legs. Detralex is widely prescribed in clinical practice as a supportive treatment for venous and lymphatic circulation disorders and can also be used in specific regimens for symptomatic management of acute and chronic hemorrhoids.

How Detralex Works

Detralex’s active micronized flavonoid fraction includes diosmin (approximately 900 mg per 1000 mg tablet) and hesperidin (about 100 mg). These compounds act synergistically to:

• Increase venous tone by improving smooth muscle contraction in vein walls.

• Enhance microcirculation and reduce venous stasis (blood pooling).

• Reduce capillary permeability and help limit fluid leakage into surrounding tissues.

• Support lymphatic drainage and decrease swelling in the legs.

• Provide angioprotective effects, strengthening capillary walls and improving blood flow through small vessels.

By optimizing these physiological processes, Detralex helps mitigate common discomforts associated with venous insufficiency and hemorrhoidal symptoms, supporting daily comfort and circulatory health.

Indications — When Detralex Is Used

Detralex 1000 mg tablets are commonly prescribed for adults to help manage symptoms related to:

Chronic Venous Insufficiency (CVI):

• Leg heaviness, pain or cramps

• Swelling of lower extremities

• Tired, fatigued legs after prolonged standing or walking

• Trophic changes of skin and subcutaneous tissues due to impaired venous return

Varicose Vein Symptoms:

• Sensation of tension, discomfort, aching or distension caused by venous dilation

Hemorrhoidal Disease (symptomatic therapy):

• Relief of pain, bleeding and inflammation during acute and chronic hemorrhoidal episodes

This dual-action profile — venotonic and angioprotective — makes Detralex a cornerstone of comprehensive venous health support when used under medical supervision.

Directions for Use

Detralex tablets are intended for oral administration and should be taken with water, preferably during meals to reduce possible gastric discomfort.

• For venous insufficiency and peripheral circulatory support: The typical regimen is 1 tablet (1000 mg) once daily with breakfast or daytime meal.

• Acute hemorrhoidal episodes: A higher initial dose is often used (e.g., 2 tablets per day, morning and evening for several days), followed by a maintenance dose as guided by a healthcare provider.

• Duration of therapy depends on clinical response and severity of symptoms; many people benefit from 3 months or longer courses, especially for chronic circulatory conditions.

Always follow the dosing instructions provided by your physician or pharmacist, as individual needs may vary.

Safety and Precautions

Detralex is suitable for adult use; it has not been established for children under 18 years.

Before starting Detralex:

• Allergies: Do not use if you are allergic to diosmin, hesperidin or any excipients.

• Pregnancy and Lactation: While animal data have not shown teratogenic effects, evidence in pregnant or nursing women is limited. Use should be discussed with a healthcare provider, particularly during breastfeeding.

• Medical Conditions: Consult your doctor if you have severe liver or kidney impairment, or other systemic conditions that might influence treatment.

Because Detralex acts on the venous system, it does not significantly affect blood pressure or heart rate; however, individuals with circulatory disorders should always consult a healthcare provider before starting therapy.

Possible Side Effects

In clinical use, Detralex is generally well tolerated, and side effects are usually mild.

Reported adverse effects may include:

• Gastrointestinal disturbances such as nausea, dyspepsia or diarrhea.

• Central nervous system reactions, including rare dizziness, headache or general malaise.

• Skin reactions such as rash, itching or urticaria, rarely.

• Very rare allergic responses, such as swelling of facial tissues or angioedema.

If severe symptoms occur or persist, discontinue use and consult a healthcare professional.

Storage and Handling

Store Detralex tablets in a cool, dry place away from direct sunlight, at temperatures below 25 °C. Keep the container tightly closed and out of reach of children. Do not use after the expiration date printed on the packaging.